Author

Patsy Tomlinson

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Biochemistry· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Albert KwokiD· 1 shared Amanda N. Sferruzzi-PerriiD· 1 shared Antonio Vidal-PuigiD· 1 shared Daniel Hart· 1 shared David A. BulgeriD· 1 shared Ilona ZvetkovaiD· 1 shared Isabel Huang-DoraniD· 1 shared Jørgen Jensen· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperBiochemistry

Albert KwokORCID

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1 paper

Recent·Most cited

C-terminal truncation of Pik3r1 in mice models human lipodystrophic insulin resistance uncoupled from dyslipidemia

Albert Kwok, Ilona Zvetkova, Sam Virtue, Isabel Huang-Doran, Patsy Tomlinson, David A. Bulger, Daniel Hart, Rachel Knox, Stephen Franks, Peter Voshol, Antonio Vidal-Puig, Amanda N. Sferruzzi-Perri, Jørgen Jensen, Stephen O’Rahilly, Robert K Semple

This study creates a mouse model of SHORT syndrome by introducing a Pik3r1 mutation, revealing lipodystrophic insulin resistance without dyslipidemia.

bioRxiv · Nov 24, 2017 · PreprintBiochemistry