Covalently linked adenovirus-AAV complexes as a novel platform technology for gene therapy
Logan Thrasher Collins, Wandy L. Beatty, Paul Boucher, Buhle Moyo, Michele Alves‐Bezerra, Ayrea E. Hurley, William R. Lagor, Gang Bao, David T. Curiel, Zhi Hong Lu
This paper introduces a novel gene therapy platform using covalently linked adenovirus-AAV complexes to improve co-infection efficiency and reduce AAV dose requirements.
bioRxiv · Aug 21, 2024 · PreprintSynthetic Biology