In vivo targeted gene delivery using Adenovirus-antibody molecular glue conjugates
Paul J. Rice-Boucher, Elena A. Kashentseva, Igor P. Dmitriev, Hongjie Guo, Jacqueline M. Tremblay, Charles B. Shoemaker, David T. Curiel, Zhi Hong Lu
This paper develops a method for targeted gene delivery using adenovirus conjugated with antibody molecular glues, showing enhanced gene transfer to specific cell types in vitro and in vivo.
bioRxiv · Jan 31, 2025 · PreprintBioengineering