Denis Seyres

Tmem127-mediated immune receptor degradation regulates T cell homeostasis through the common gamma chain

The paper identifies Tmem127 as a regulator of T cell homeostasis by controlling IL-7 receptor surface expression and common gamma chain interactions.

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.

The paper identifies molecular and metabolic signatures of cardiometabolic syndrome using extreme phenotype groups and shows changes after bariatric surgery.

Genetic Analyses of Blood Cell Structure for Biological and Pharmacological Inference

This study performs GWAS on blood cell flow-cytometry phenotypes, identifies variant-trait associations, and links them to cellular structures and disease mechanisms.

Cell type specific novel lincRNAs and circRNAs in the BLUEPRINT haematopoietic transcriptomes atlas.

The paper identifies novel long non-coding RNAs and circular RNAs in hematopoietic cells using BLUEPRINT consortium data, highlighting their cell type specificity.

Histone Acetyltransferase Kat2a Stabilises Pluripotency with Control of Transcriptional Heterogeneity

The paper shows that inhibiting Kat2a increases transcriptional heterogeneity in mouse embryonic stem cells, leading to reduced pluripotency and accelerated differentiation.