Author

Aleix Noguera‐Castells

Instituto de Salud Carlos IIIORCID 0000-0001-7436-6513Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Assay:metabolomics· 1 Assay:metagenomics· 1

Frequent Co-Authors

Manel EstelleriD· 3 shared Raquel PluvinetiD· 2 shared Alba Royo-GarcíaiD· 1 shared Alberto Bueno-CostaiD· 1 shared Aleix LluansíiD· 1 shared Ana Galván-del-ReyiD· 1 shared Ángel RomániD· 1 shared Annika Patthey· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Manel EstellerORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintFeb 14, 2026

High-fat diet imprints a macrophage-tumor CAMP-P2RX7 axis driving pancreatic cancer initiation, plasticity and metastasis

Ana Galván-del-Rey, Juan Carlos López-Gil, Livia Archibugi…·Carmen Guerra

This study identifies a diet-imprinted macrophage-tumor circuit driven by the CAMP-P2RX7 axis that promotes pancreatic cancer initiation, plasticity, and metastasis.

1 citation

mouseexperimental assay

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Cancer BiologybioRxivPreprintSep 10, 2025

METTL3-mediated m6A modification of DNMT1 enhances ovarian cancer progression

Kanchan Kumari, Iván Pérez-Núñez, Aleix Noguera‐Castells…·Francesca Aguiló

This study identifies METTL3-mediated m6A modification of DNMT1 as a driver of ovarian cancer progression by enhancing DNMT1 translation and suppressing tumor suppressors.

DOI 10.1101/2025.09.10.675425

humanDNA methylation

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GenomicsbioRxivPreprintFeb 24, 2025

The Multiomics Blueprint of Extreme Human Lifespan

Eloy Santos-Pujol, Aleix Noguera‐Castells, Marta Casado-Peláez…·Manel Esteller

This study presents a multi-omics analysis of a supercentenarian, revealing that extreme age and poor health are distinct molecular processes.

2 citations

humanwhole-genome sequencing

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