Synchrotron XRF imaging reveals manganese accumulation in the Golgi and post-synapses of neurons and enhanced uptake in astrocytes
Ines Kelkoul, Aiyarin Kittilukkana, Luis C.C. Huarte, Hiram A. Castillo-Michel, M. Salome-Pateyron, Stéphane Roudeau, Pauline Belzanne, Matthieu Sainlos, Noémie Pied, Mónica Fernández‐Monreal, Daniel Choquet, Richard Ortega, Asunción Carmona
This study uses synchrotron XRF imaging to show manganese accumulates in the Golgi and postsynapses of neurons and astrocytes, with astrocytes taking up more manganese and reducing neuronal uptake.
Advanced Science · Apr 9, 2026Peer-reviewedNeuroscience