Sophie Daburon

βII and βIII spectrin paralogues define robustness and specialization of the neuronal membrane periodic skeleton

The paper shows that βII and βIII spectrin paralogues form a dual system in the dendritic MPS, with structural redundancy and paralogue-specific regulation.

A nanobody-gold conjugate for the detection of GFP-tagged synaptic proteins by dual light-electron microscopy

The paper develops a nanobody-gold conjugate for dual light-electron microscopy to label GFP-tagged synaptic proteins with high specificity and nanoscale resolution.

Paralog-specific intrabodies for PSD-93 and SAP102 expand the molecular toolkit to resolve excitatory synapse organization

The paper develops paralog-specific intrabodies for PSD-93 and SAP102 to study excitatory synapse organization.

Synapse specific and plasticity-regulated AMPAR mobility tunes synaptic integration

The paper investigates how AMPAR surface diffusion and desensitization contribute to frequency-dependent synaptic adaptation during high-frequency stimulation.

High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning

This study uses a knock-in mouse model to monitor and manipulate AMPA receptor mobility, showing its role in synaptic plasticity and memory formation.

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

The paper shows MDGAs delay excitatory synapse development by altering neuroligin behavior through fast diffusion and reduced mobility.

Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plasticity and memory in Huntington’s disease

This study shows that impaired AMPA receptor surface diffusion contributes to synaptic plasticity and memory deficits in Huntington’s disease, and that tianeptine can restore these functions.