Isabelle Jansen

The paper shows that βII and βIII spectrin paralogues form a dual system in the dendritic MPS, with structural redundancy and paralogue-specific regulation.

The paper uses 3D MINFLUX and DNA-PAINT to determine the orientation of Bassoon at active zones with 5 nm precision, showing its C-terminal faces the synaptic cleft and N-terminal faces synaptic vesicles.

The paper uses MINFLUX nanoscopy to visualize the molecular architecture of the photoreceptor active zone, revealing a serially duplicated complex of bassoon-RIM2-ubMunc13-2-CAST.