Spatial positioning of preimplantation mouse embryo blastomeres is regulated by mTORC1 and 7mG-cap dependent translation at the 8- to 16-cell transition.
Lenka Gahurová, Jana Tománková, Pavlina Cerna, Pablo Bora, Michaela Kubičková, Giorgio Virnicchi, Kristina Kovacicova, David Potěšil, Pavel Hruška, Zbyněk Zdráhal, Martin Anger, Andrej Šušor, Alexander W. Bruce
The paper identifies mTORC1 and 7mG-cap dependent translation as regulators of spatial positioning of blastomeres during the 8- to 16-cell transition in mouse embryos.
bioRxiv · Mar 7, 2023 · PreprintDevelopmental Biology