Alexander W. Bruce

This study shows TEAD4 maintains trophectoderm lineage integrity by regulating apical domain morphology and cell positioning in mouse preimplantation embryos.

The paper investigates whether p38-MAPK inhibition affects primitive endoderm differentiation in mouse blastocysts through ICM autonomous mechanisms or cavity expansion defects.

The paper identifies mTORC1 and 7mG-cap dependent translation as regulators of spatial positioning of blastomeres during the 8- to 16-cell transition in mouse embryos.

This study investigates the role of DDX21 in mouse preimplantation embryo development, showing its necessity for cell-fate specification and blastocyst formation through p38-MAPK regulation.

This study shows that p38-MAPK regulates PrE differentiation during mouse blastocyst maturation by controlling translation and rRNA processing through Mybpp1a.

This study identifies Wwc2 as a regulator of cell division during mouse preimplantation embryo development and oogenesis, showing its role in maintaining cell number and division fidelity.

The paper shows that p38-MAPK regulates blastocyst development in response to amino acid availability and oxidative stress, affecting cell lineage specification and blastocyst size.