VAMP8 function reveals tight linkage between endocytic recycling and endocytosis
Ailing Liu, Yueping Li, Zheng Huang, Wenxing Chen, Peiliu Xu, Xiangying Wei, Guosheng Hu, Shuangquan Liu, Xiaoxia Liu, Yan He, Danling Wang, Sandra L. Schmid, Zhiming Chen
This study shows that VAMP8 depletion impairs clathrin-mediated endocytosis by disrupting endocytic cargo recycling and rerouting it to lysosomal degradation.
Proceedings of the National Academy of Sciences · Mar 26, 2026Peer-reviewedCell Biology