Large vesicle extrusions from C. elegans neurons are consumed and stimulated by glial-like phagocytosis activity of the neighboring cell
Yu Wang, Meghan Lee Arnold, Anna Joelle Smart, Guoqiang Wang, Rebecca J. Androwski, Andrés Morera, Ken C. Q. Nguyen, Peter J. Schweinsberg, Ge Bai, Jason F. Cooper, David H. Hall, Monica Driscoll, Barth D. Grant
The paper investigates the fate of exophers in C. elegans, showing they are engulfed and degraded by hypodermal cells through a phagocytic process involving specific molecular factors.
eLife · Mar 2, 2023Peer-reviewedNeuroscience