RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubík, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castelló, Gracjan Michlewski
This study identifies the PRY/SPRY domain of TRIM25 as its RNA-binding region and shows its role in ubiquitination.
BMC Biology · Nov 8, 2017Peer-reviewedMolecular Biology