Author

Pontian Adogamhe

Indiana University Indianapolis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Aaron Snow· 2 shared Angelia D. LockettiD· 2 shared Marta Teixeira Gomes· 2 shared Roberto F. MachadoiD· 2 shared Amanda Jo Fisher· 1 shared Justin R. Sysol· 1 shared Manas Yadav· 1 shared Micheala A. AldrediD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

Aaron Snow

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2 papers

Recent·Most cited

Nicotinamide phosphoribosyltransferase activates the mitochondrial unfolded protein response to promote pulmonary arterial endothelial cell proliferation

Angelia D. Lockett, Pontian Adogamhe, Aaron Snow, Marta Teixeira Gomes, Roberto F. Machado

This study shows that Nampt activates the mitochondrial unfolded protein response to enhance pulmonary arterial endothelial cell proliferation in PAH.

bioRxiv · Jan 16, 2026 · PreprintCell Biology

The mitochondrial unfolded protein response and metabolic reprogramming promote PASMC proliferation in response to sphingosine kinase-1/sphingosine-1-phosphate signaling

Angelia D. Lockett, Aaron Snow, Pontian Adogamhe, Justin R. Sysol, Manas Yadav, Tendo Mubuuke, Marta Teixeira Gomes, Todd G. Cook, Amanda Jo Fisher, Micheala A. Aldred, Roberto F. Machado

This study shows that the Sphk1/S1P/S1P2 signaling axis promotes PASMC proliferation in PAH via activation of the mitochondrial unfolded protein response (UPRmt), which can be inhibited to reduce vascular remodeling.

bioRxiv · Jun 10, 2025 · PreprintCell Biology