Author

Tendo Mubuuke

Indiana University Indianapolis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Aaron Snow· 1 shared Amanda Jo Fisher· 1 shared Angelia D. LockettiD· 1 shared Justin R. Sysol· 1 shared Manas Yadav· 1 shared Marta Teixeira Gomes· 1 shared Micheala A. AldrediD· 1 shared Pontian Adogamhe· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Aaron Snow

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1 paper

Recent·Most cited

The mitochondrial unfolded protein response and metabolic reprogramming promote PASMC proliferation in response to sphingosine kinase-1/sphingosine-1-phosphate signaling

Angelia D. Lockett, Aaron Snow, Pontian Adogamhe, Justin R. Sysol, Manas Yadav, Tendo Mubuuke, Marta Teixeira Gomes, Todd G. Cook, Amanda Jo Fisher, Micheala A. Aldred, Roberto F. Machado

This study shows that the Sphk1/S1P/S1P2 signaling axis promotes PASMC proliferation in PAH via activation of the mitochondrial unfolded protein response (UPRmt), which can be inhibited to reduce vascular remodeling.

bioRxiv · Jun 10, 2025 · PreprintCell Biology