Aging reshapes cardiac extravascular leukocyte transcription through bidirectional remodeling during LPS-induced endotoxemia
Qing Yu, Hongyu Gao, Fang Fang, Jiayue Du, Meijing Wang
This study shows aging causes bidirectional transcriptional changes in cardiac immune cells during LPS-induced endotoxemia, with shared mitochondrial remodeling and cell-type-specific functional shifts.
bioRxiv · Nov 3, 2026 · PreprintBioinformatics