Author

Patrícia Gomes

University of MinhoORCID 0000-0001-7130-3445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Clarissa L. WaitesiD· 3 shared Ioannis SotiropoulosiD· 3 shared Joana Margarida SilvaiD· 2 shared João Vaz‐SilvaiD· 2 shared Mei J. ZhuiD· 2 shared Nuno SousaiD· 2 shared Viktoriya ZhuravlevaiD· 2 shared Carina Soares‐CunhaiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Clarissa L. WaitesORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedJan 18, 2024

Glucocorticoid stress hormones stimulate vesicle-free Tau secretion and spreading in the brain

Qing Yu, Fang Du, Irla Belli…·Clarissa L. Waites

This study shows that glucocorticoids promote vesicle-free Tau secretion and trans-neuronal Tau spreading in the brain, contributing to Alzheimer's disease progression.

10 citations

mouseproteomics

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NeuroscienceCell Death and DiseasePeer-reviewedDec 7, 2021

Rab35 and glucocorticoids regulate APP and BACE1 trafficking to modulate Aβ production

Viktoriya Zhuravleva, João Vaz‐Silva, Mei J. Zhu…·Clarissa L. Waites

This study shows Rab35 regulates APP and BACE1 trafficking to reduce Aβ production, and its downregulation by stress and aging contributes to amyloidogenesis.

25 citations

mouseexperimental assay

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NeuroscienceThe EMBO JournalPeer-reviewedAug 30, 2018

Endo-lysosomal sorting and degradation of Tau mediates glucocorticoid-driven hippocampalmalfunction

João Vaz‐Silva, Patrícia Gomes, Qi Jin…·Clarissa L. Waites

This study shows that glucocorticoids impair Tau degradation via the Rab35/ESCRT pathway, leading to Tau accumulation and hippocampal dysfunction.

105 citationstop 2%

mouseexperimental assay

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