Jeffrey H. Goodman

This study shows APOE4 worsens stress hormone-induced tau pathology in the hippocampus through mitochondrial dysfunction and identifies a potential therapeutic target.

This study demonstrates efficient brain-specific delivery of FMR1 via AAVphp vectors in adult FMR1 KO mice, leading to partial behavioral improvements and increased FMRP levels.

This study shows that persistent increases in PKMζ in specific layers of the sensorimotor cortex are necessary for maintaining long-term procedural memories in rats.