Author

R. A. Porritt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

I. Bahar· 3 shared M. Arditi· 3 shared M. H. Cheng· 3 shared M. Noval Rivas· 2 shared A. B. Ozdemir· 1 shared A. Fasano· 1 shared B. C. Fries· 1 shared C. Santiskulvong· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersImmunology

I. Bahar

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Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivNov 24, 2020

A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro

M. H. Cheng, R. A. Porritt, M. Noval Rivas…·I. Bahar

This paper shows that an anti-SEB monoclonal antibody inhibits SARS-CoV-2 entry by blocking protease access to the Spike protein's cleavage site.

DOI 10.1016/j.str.2021.04.005

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintNov 9, 2020

Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome

R. A. Porritt, L. Paschold, M. Noval Rivas…·M. Arditi

This study identifies a skewed TCR repertoire in MIS-C patients, with TRBV11-2 expansion linked to disease severity and superantigen-like interactions with SARS-CoV-2 spike protein.

DOI 10.1101/2020.11.09.372169

𝕏 PostBluesky

ImmunologybioRxivMay 21, 2020

An insertion unique to SARS-CoV-2 exhibits superantigenic character strengthened by recent mutations

M. H. Cheng, S. Zhang, R. A. Porritt…·I. Bahar

The paper identifies a SARS-CoV-2 spike protein motif with superantigen-like properties that may contribute to MIS-C and cytokine storms in COVID-19 patients.

DOI 10.1073/pnas.2010722117

virusproteomics

𝕏 PostBluesky