Author

R. Abdalkader

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 3 Assay:metabolomics· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

K.-i. Kamei· 4 shared R. Chaleckis· 3 shared C. Wheelock· 2 shared I. Meister· 1 shared P. Zhang· 1 shared T. Fujita· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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4 shared papersBioengineering

K.-i. Kamei

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5 papers

Recent·Most cited

Early Differentiation Signatures in Human Induced Pluripotent Stem Cells Determined by Non-Targeted Metabolomics Analysis

R. Abdalkader, R. Chaleckis, T. Fujita

This study uses non-targeted metabolomics to identify early differentiation signatures in hiPSCs during ectodermal lineage commitment, showing changes in metabolites like pyruvic acid and kynurenine.

bioRxiv · Mar 2, 2023 · PreprintBioengineering

An efficient simplified method for the generation of corneal epithelial cells from human pluripotent stem cells

R. Abdalkader, K.-i. Kamei

This paper introduces a simplified small molecule-based method to generate functional corneal epithelial cells from human pluripotent stem cells, showing improved differentiation and metabolic characteristics.

bioRxiv · Jan 16, 2022Bioengineering

Spatiotemporal Determination of Metabolite Activities in Multiple Corneal Epithelium Barriers on a Chip

R. ABDALKADER, R. Chaleckis, C. Wheelock, K.-i. Kamei

This study introduces Cornea-Chip to analyze spatiotemporal metabolite dynamics in corneal epithelium barriers using metabolomics and mRNA analysis.

bioRxiv · Jan 8, 2021Bioengineering

Untargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes

R. Abdalkader, R. Chaleckis, I. Meister, P. Zhang, C. Wheelock, K.-i. Kamei

The paper develops an LC-MS-based untargeted metabolomics protocol to analyze micro-scale extracellular metabolites from hepatocytes and identifies metabolite shifts over time.

bioRxiv · Sep 24, 2020Bioengineering

Multi-corneal barriers-on-a-chip to recapitulate eye blinking shear stress forces

R. Abdalkader, K.-i. Kamei

This paper develops a microfluidic platform to simulate eye blinking shear stress on human corneal epithelial cells, showing enhanced barrier function under flow conditions.

bioRxiv · Dec 23, 2019Bioengineering