Author

R. Chaleckis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:metabolomics· 4 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

K.-i. Kamei· 3 shared R. Abdalkader· 3 shared C. Wheelock· 2 shared T. Fujita· 2 shared I. Meister· 1 shared P. Zhang· 1 shared R. K. Abdalkader· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 14 mutual co-author links

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3 shared papersBioengineering

K.-i. Kamei

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4 papers

Recent·Most cited

Modeling dry eye with an air-liquid interface in corneal epithelium-on-a-chip

R. K. Abdalkader, R. Chaleckis, T. Fujita, K.-i. Kamei

This study modifies a corneal epithelium-on-a-chip model to simulate dry eye syndrome by applying an air-liquid interface stimulus and assesses its effects with and without diclofenac.

bioRxiv · Oct 8, 2023Bioengineering

Early Differentiation Signatures in Human Induced Pluripotent Stem Cells Determined by Non-Targeted Metabolomics Analysis

R. Abdalkader, R. Chaleckis, T. Fujita

This study uses non-targeted metabolomics to identify early differentiation signatures in hiPSCs during ectodermal lineage commitment, showing changes in metabolites like pyruvic acid and kynurenine.

bioRxiv · Mar 2, 2023 · PreprintBioengineering

Spatiotemporal Determination of Metabolite Activities in Multiple Corneal Epithelium Barriers on a Chip

R. ABDALKADER, R. Chaleckis, C. Wheelock, K.-i. Kamei

This study introduces Cornea-Chip to analyze spatiotemporal metabolite dynamics in corneal epithelium barriers using metabolomics and mRNA analysis.

bioRxiv · Jan 8, 2021Bioengineering

Untargeted LC-MS metabolomics for the analysis of micro-scaled extracellular metabolites from hepatocytes

R. Abdalkader, R. Chaleckis, I. Meister, P. Zhang, C. Wheelock, K.-i. Kamei

The paper develops an LC-MS-based untargeted metabolomics protocol to analyze micro-scale extracellular metabolites from hepatocytes and identifies metabolite shifts over time.

bioRxiv · Sep 24, 2020Bioengineering