A pressure sensing protein kinase
R. Akella, K. Sekulski, J. M. Pleinis, J. Liwocha, J. Jiou, H. He, J. M. Humphreys, J. N. Schellinger, J. Hu, M. H. Cobb, L. Joachimiak, A. R. Rodan, E. J. Goldsmith
This paper identifies WNK3 as a direct hydrostatic pressure sensor, showing pressure-induced dimer-to-monomer transition and activation in D. melanogaster.
bioRxiv · Mar 11, 2019 · PreprintBiophysics