Author

K. Sekulski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Organism:Drosophila· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

J. P. Erzberger· 2 shared A. R. Rodan· 1 shared C. S. Weirich· 1 shared C. Sailer· 1 shared C. Weirich· 1 shared E. J. Goldsmith· 1 shared F. Stengel· 1 shared H. He· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

J. P. Erzberger

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Author profile →

3 papers

Recent·Most cited

rRNA methylation by Spb1 regulates the GTPase activity of Nog2 during 60S ribosomal subunit assembly

K. Sekulski, V. E. Cruz, C. S. Weirich, J. P. Erzberger

This study shows that rRNA methylation by Spb1 regulates Nog2 GTPase activity during 60S ribosome assembly, revealing a kinetic checkpoint mechanism.

bioRxiv · May 25, 2022Biophysics

Sequence-directed RNA remodeling within a topologically complex RNP substrate

V. Cruz Ruiz, K. Sekulski, N. Peddada, C. Sailer, S. Balasubramanian, C. Weirich, F. Stengel, J. P. Erzberger

The paper describes cryo-EM structures of 60S ribosomal intermediates, showing how DEAD-box ATPase Spb4 drives sequence-directed RNA remodeling during RNP assembly.

bioRxiv · Feb 24, 2022Biophysics

A pressure sensing protein kinase

R. Akella, K. Sekulski, J. M. Pleinis, J. Liwocha, J. Jiou, H. He, J. M. Humphreys, J. N. Schellinger, J. Hu, M. H. Cobb, L. Joachimiak, A. R. Rodan, E. J. Goldsmith

This paper identifies WNK3 as a direct hydrostatic pressure sensor, showing pressure-induced dimer-to-monomer transition and activation in D. melanogaster.

bioRxiv · Mar 11, 2019 · PreprintBiophysics