Author

F. Bieberich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Organism:human· 5 Assay:scRNA-seq· 4 Approach:deep learning· 3 Research Focus:differential expression· 3 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

R. Vazquez-Lombardi· 5 shared S. T. Reddy· 5 shared A. Yermanos· 3 shared C. R. Weber· 3 shared E. Kapetanovic· 3 shared B. Wagner· 2 shared D. M. Mason· 2 shared F. Rudolf· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

R. Vazquez-Lombardi

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Author profile →

5 papers

Recent·Most cited

Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer

F. Bieberich, R. Vazquez-Lombardi, H. Jin, K.-L. Hong, P. Herzig, M. Trefny, M. Trueb, H. Laubli, D. Lardinois, K. Mertz, M. Matter, A. Zippelius, S. T. Reddy

This study uses multimodal single-cell profiling to analyze T cell specificity and reactivity in lung cancer patients, identifying tumor- and virus-reactive T cells and their functional states.

bioRxiv · Oct 4, 2023 · PreprintImmunology

A single-cell atlas of lymphocyte adaptive immune repertoires and transcriptomes reveals age-related differences in convalescent COVID-19 patients

F. Bieberich, R. Vazquez-Lombardi, A. Yermanos, R. A. Ehling, D. M. Mason, B. Wagner, E. Kapetanovic, R. B. Di Roberto, C. R. Weber, M. Savic, F. Rudolf, S. T. Reddy

This study uses single-cell sequencing to analyze immune repertoires and transcriptomes in convalescent COVID-19 patients, revealing age-related differences in T and B cell responses.

bioRxiv · Feb 12, 2021Immunology

Single-cell sequencing of plasma cells from COVID-19 patients reveals highly expanded clonal lineages produce specific and neutralizing antibodies to SARS-CoV-2

R. A. Ehling, C. R. Weber, D. M. Mason, S. Friedensohn, B. Wagner, F. Bieberich, E. Kapetanovic, R. Vazquez-Lombardi, R. B. Di Roberto, K.-L. Hong, C. Wagner, D. J. Sheward, B. Murrell, A. Yermanos, A. Cuny, , S. T. Reddy

Single-cell sequencing and screening identify expanded plasma cell clones in COVID-19 patients producing SARS-CoV-2-specific neutralizing antibodies.

bioRxiv · Feb 12, 2021 · PreprintImmunology

Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes

A. Yermanos, A. Agrafiotis, J. Yates, C. Papadopoulou, D. Robbiani, F. Bieberich, R. Vazquez-Lombardi, D. Neumeier, A. Oxenius, S. T. Reddy

Platypus integrates single-cell immune repertoires with transcriptomes to analyze lymphocyte features and transcriptional profiles in convalescent COVID-19 patients.

bioRxiv · Nov 9, 2020Immunology

CRISPR-targeted display of functional T cell receptors enables engineering of enhanced specificity and prediction of cross-reactivity

R. Vazquez-Lombardi, J. Jung, F. Bieberich, E. Kapetanovic, E. Aznauryan, C. R. Weber, S. T. Reddy

The paper introduces a CRISPR-based platform to engineer TCRs with enhanced specificity and predict cross-reactivity by profiling mutational landscapes and screening TCR libraries.

bioRxiv · Jun 23, 2020 · PreprintImmunology