Modular assembly of mitochondrial complex III from a dynamic matrix domain pool
J. Jimenez-Niebla, R. Jha, C. Wirth, J. V. Busto, A. Feignier, M. Cosenza-Contreras, K. Ruoff, M. Dorer, R. Babic, F. Drepper, C. Kraft, P. F. Huesgen, N. Wiedemann, W.-C. Kao, Carola Hunte
This study reveals how mitochondrial complex III assembles from preformed matrix domain modules, showing dynamic subunit exchange and the role of specific residues in assembly and disease.
bioRxiv · Nov 9, 2026 · PreprintBiochemistry