Author

R. Jha

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Alnasser· 1 shared A. B. Kumar· 1 shared A. Feignier· 1 shared A. M. Amitrano· 1 shared A. Sammarco· 1 shared B. Acharya· 1 shared B. K. Lal· 1 shared B. P. Upadhyaya· 1 shared

Activity by Year

2017-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

A. Alnasser

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Modular assembly of mitochondrial complex III from a dynamic matrix domain pool

J. Jimenez-Niebla, R. Jha, C. Wirth, J. V. Busto, A. Feignier, M. Cosenza-Contreras, K. Ruoff, M. Dorer, R. Babic, F. Drepper, C. Kraft, P. F. Huesgen, N. Wiedemann, W.-C. Kao, Carola Hunte

This study reveals how mitochondrial complex III assembles from preformed matrix domain modules, showing dynamic subunit exchange and the role of specific residues in assembly and disease.

bioRxiv · Nov 9, 2026 · PreprintBiochemistry

Divergent MEK/ERK and AMPK signaling dictate lipogenic plasticity and dependence on fatty acid synthesis in Glioblastoma

K. Eyme, A. Sammarco, R. Jha, H. MNATSAKANYAN, R. Neustadt, C. Moses, A. Alnasser, D. Tardiff, B. Su, K. Williams, S. Bensinger, C. Y. Chung, c. E. badr

This study identifies that MEK/ERK and AMPK signaling regulate lipogenic plasticity in Glioblastoma stem-like cells, influencing their dependence on fatty acid synthesis and response to DNLS inhibitors.

bioRxiv · Apr 7, 2022 · PreprintCancer Biology

Three-dimensional microenvironment regulates gene expression, function, and tight junction dynamics of iPSC-derived blood-brain barrier microvessels

R. M. Linville, M. B. Sklar, G. N. Grifno, R. F. Nerenberg, J. Zhou, R. Ye, J. G. DeStefano, Z. Guo, R. Jha, J. J. Jamieson, N. Zhao, P. C. Searson

This study shows that a 3D microenvironment enhances BBB phenotype and function in iPSC-derived microvessels compared to 2D cultures.

bioRxiv · Aug 27, 2021Bioengineering

CD49a Identifies Polyfunctional Memory CD8 T cell Subsets that Persist in the Lungs after Influenza Infection

E. C. Reilly, M. Sportiello, K. Lambert Emo, A. M. Amitrano, R. Jha, A. B. Kumar, N. G. Laniewski, H. Yang, M. Kim, D. J. Topham

This study identifies CD49a-expressing polyfunctional CD8 memory subsets in lung tissue that persist after influenza infection and exhibit diverse effector functions.

bioRxiv · Jul 30, 2021Immunology

Confirmation of local transmission of Orientia tsutsugamushi during scrub typhus outbreaks in Nepal

M. Dhimal, S. P. Dumre, G. N. Sharma, P. Khanal, K. Ranabhat, L. P. Shah, B. K. Lal, R. Jha, B. P. Upadhyaya, B. Acharya, S. K. Shrestha, S. A. Davidson, P. Charoensinphon, K. B. Karki

This study confirms local transmission of Orientia tsutsugamushi in Nepal by detecting the pathogen in humans, rodents, and chigger mites during scrub typhus outbreaks.

bioRxiv · Nov 22, 2019 · PreprintPathology

Combinatorial Regulation Of The Balance Between Dynein Microtubule End Accumulation And Initiation Of Directed Motility

R. Jha, J. Roostalu, M. Trokter, T. Surrey

The paper investigates how dynein activity is regulated by different regulators, revealing distinct pools of dynein with opposing preferences for binding regulators and different motility behaviors.

bioRxiv · Apr 11, 2017Cell Biology