Immunodominant surface epitopes power immune evasion in the African trypanosome
A. Gkeka, F. Aresta-Branco, G. Triller, E. P. Vlachou, M. Lilic, P. D. B. Olinares, K. Perez, B. Chait, R. Blatnik, T. Ruppert, C. E. Stebbins, F. N. Papavasiliou
The paper shows that immune responses to African trypanosome VSGs are focused on immunodominant epitopes, enabling immune evasion through epitope variation.
bioRxiv · Jul 20, 2021Immunology