Author

R. Bonomo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Research Focus:drug response / drug discovery· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Anderson· 1 shared A. E. Sheppard· 1 shared A. M. Hujer· 1 shared A. Mathers· 1 shared A. S. Walker· 1 shared A. Vaughan· 1 shared C. Bryant· 1 shared D. Griffiths· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperEvolutionary Biology

A. Anderson

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2 papers

Recent·Most cited

Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli

T. J. Davies, N. Stoesser, A. E. Sheppard, M. Abuoun, P. W. Fowler, J. Swann, P. Quan, D. Griffiths, A. Vaughan, M. Morgan, H. T. T. Phan, K. J. Jeffery, M. Andersson, M. Ellington, O. Ekelund, , A. S. Walker

This study shows that amoxicillin-clavulanate resistance in E. coli is quantitative, not binary, and that WGS-based predictions outperform traditional phenotyping methods.

bioRxiv · Feb 6, 2020Microbiology

Antibiotic collateral sensitivity is contingent on the repeatability of evolution

D. Nichol, J. Rutter, C. Bryant, A. M. Hujer, S. Lek, M. D. Adams, P. Jeavons, A. Anderson, R. Bonomo, J. Scott

This study shows that sequential antibiotic treatments may overestimate therapeutic benefits due to stochastic resistance or susceptibility outcomes in E. coli.

bioRxiv · Jan 9, 2019Evolutionary Biology