Discordance between different bioinformatic methods for identifying resistance genes from short-read genomic data, with a focus on Escherichia coli
T. J. Davies, J. Swann, A. E. Sheppard, H. Pickford, S. Lipworth, M. AbuOun, M. Ellington, P. W. Fowler, S. Hopkins, K. Hopkins, D. Crook, T. E. Peto, M. F. Anjum, A. S. Walker, N. Stoesser
This study evaluates four AMR gene typing methods using simulated and real E. coli data, revealing significant discrepancies and highlighting issues with current bioinformatic approaches.
bioRxiv · Nov 3, 2021 · PreprintMicrobiology