Author

R. C. Arend

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Mythreye· 3 shared N. Hempel· 3 shared A. K. Shelton· 2 shared A. S. Choi· 2 shared C. R. Miller· 2 shared D. Altomare· 2 shared M. D. Starr· 2 shared M. Monavarian· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

K. Mythreye

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling.

A. S. Choi, L. M. Jenkins-Lane, W. Barton, A. Kumari, C. Lancaster, C. Raulerson, H. Ji, D. Altomare, M. D. Starr, R. Whitaker, R. Phaeton, R. C. Arend, M. Shtutman, A. B. Nixon, N. Hempel, , K. Mythreye

This study identifies heparan sulfate modifications as critical for betaglycan ectodomain shedding, which regulates TGF-β signaling and has clinical implications in ovarian cancer.

bioRxiv · Aug 29, 2023 · PreprintBiochemistry

PVT1, a YAP1 dependent stress responsive lncRNA drives ovarian cancer metastasis and chemoresistance

K. Tabury, M. Monavarian, E. Listik, A. K. Shelton, A. S. Choi, R. Quintens, R. C. Arend, N. Hempel, C. R. Miller, B. Györrfy, K. Mythreye

This study identifies PVT1, a YAP1-dependent stress-responsive lncRNA that promotes ovarian cancer metastasis and chemoresistance, suggesting it as a therapeutic target.

bioRxiv · Jan 11, 2022 · PreprintCancer Biology

Reciprocal epigenetic Sox2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer

Z. SHONIBARE, M. Monavarian, K. O'Connell, D. Altomare, A. K. Shelton, S. Mehta, R. Jaskula-Sztul, R. Phaeton, M. D. Starr, R. Whitaker, A. Berchuck, A. Nixon, R. C. Arend, N. Y. Lee, C. R. Miller, , K. Mythreye

This study identifies Sox2 as a key node regulated by opposing TGF-β superfamily signals, impacting anoikis resistance and metastasis in ovarian cancer.

bioRxiv · Jan 11, 2022Cancer Biology