Author

R. Castro-Portuguez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

A. B. Antenor· 1 shared A. E. Haskins· 1 shared A. Grant· 1 shared A. W. Watson· 1 shared B. Hull· 1 shared B. L. Forte· 1 shared C. C. Gowan· 1 shared C. Franck· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. B. Antenor

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Author profile →

2 papers

Recent·Most cited

The Emerging Role of 3-Hydroxyanthranilic Acid on C. elegans Aging Immune Function

L. S. Espejo, D. D. DeNicola, L. M. Chang, V. D. Silbar, A. E. Haskins, A. B. Antenor, J. r. Balsa, S. Freitas, S. Hamming, B. Hull, H. Dang, R. Castro-Portuguez, G. L. Sutphin

This paper investigates how 3HAA and haao-1 inhibition affect C. elegans immune function and aging, finding that 3HAA improves immune function and acts as an antimicrobial against gram-negative bacteria.

bioRxiv · Jan 7, 2024 · PreprintImmunology

Breast tumor stiffness instructs bone metastasis via mechanical memory

A. W. Watson, A. Grant, S. S. Parker, M. W. Harman, M. R. Roman, B. L. Forte, C. C. Gowan, R. Castro-Portuguez, C. Franck, D. Cusanovich, M. Padi, C. Romanoski, G. Mouneimne

This study shows that primary tumor stiffness induces stable mechanical memory in breast cancer cells, promoting bone metastasis through ERK-RUNX2 signaling and a MeCo score.

bioRxiv · Nov 20, 2019 · PreprintCancer Biology