Author

R. Cavill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:drug response / drug discovery· 3 Approach:statistical model· 3 Assay:clinical cohort / trial· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

K. Stankova· 4 shared K. Schneider· 2 shared M. Salvioli· 2 shared A. Kaznatcheev· 1 shared A. Soboleva· 1 shared C. G. Hubert· 1 shared C. Lokh· 1 shared F. Thuijsman· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersCancer Biology

K. Stankova

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Author profile →

4 papers

Recent·Most cited

Validation of polymorphic Gompertzian model of cancerthrough in vitro and in vivo data

A. Soboleva, A. Kaznatcheev, R. Cavill, K. Schneider, K. Stankova

This study validates the polymorphic Gompertzian model using in vitro and in vivo NSCLC data, showing it captures tumor dynamics and relapse trends better than classical models.

bioRxiv · Apr 19, 2023 · PreprintCancer Biology

How to use transcriptomic data for game-theoretic modeling of treatment-induced resistance in cancer cells? A case study in patient-derived glioblastoma organoids

L. Spekking, C. Lokh, W. Jung, M. Verduin, S. Azimi, C. G. Hubert, M. Vooijs, R. Cavill, K. Stankova

This paper uses transcriptomic data from glioblastoma organoids to predict evolutionary responses to irradiation using game-theoretic models, finding hypoxia drives short-term resistance while supervised methods best estimate evolutionary dynamics.

bioRxiv · Jan 26, 2022 · PreprintCancer Biology

Improving Mathematical Models of Cancer throughGame-Theoretic Modelling: A Study in Non-SmallCell Lung Cancer

V. Ardevol Martinez, N. Ghaffari Laleh, M. Salvioli, F. Thuijsman, J. S. Brown, R. Cavill, J. N. Kather, K. Stankova

This study applies a game-theoretic model to 590 Non-Small Cell Lung Cancer patients, showing it better fits tumor dynamics than classical models and predicts treatment outcomes.

bioRxiv · Oct 29, 2021 · PreprintCancer Biology

Is the Success of Adaptive Therapy in Metastatic Castrate Resistant Prostate Cancer Influenced by Cell-Type-Dependent Production of Prostate Specific Antigen?

M. Salvioli, L. Vandelaer, K. Schneider, R. Cavill, K. Stankova

This study evaluates how different cell-type contributions to PSA production affect the success of adaptive therapy in metastatic castrate-resistant prostate cancer.

bioRxiv · Oct 21, 2021 · PreprintCancer Biology