The Vibrio cholerae cytotoxin MakA induces noncanonical autophagy resulting in the spatial inhibition of canonical autophagy
D. Corkery, A. Nadeem, K. M. Aung, A. Hassan, T. Liu, R. Cervantes-Rivera, A. H. Lystad, H. Wang, K. Persson, A. Puhar, A. Simonsen, B. E. Uhlin, S. N. Wai, Y. Wu
This study shows that Vibrio cholerae toxin MakA induces noncanonical autophagy, which inhibits canonical autophagy and immune responses like IL-1β secretion.
bioRxiv · Jul 7, 2020Cell Biology