Author

R. Chandwani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Assay:ChIP-seq· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Cardenas· 1 shared A. F. Rendeiro· 1 shared A. Grimont· 1 shared A. L. Massa· 1 shared A. Osterhoudt· 1 shared A. P. Makohon-Moore· 1 shared A. Tarakhovsky· 1 shared B. Curry· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCancer Biology

A. Cardenas

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Author profile →

3 papers

Recent·Most cited

Control of enhancer activation in the type I interferon response by the histone demethylase Kdm4d/JMJD2d

R. Chandwani, T. C. Fang, S. Dewell, A. Tarakhovsky

This study identifies Kdm4d/JMJD2d as a positive regulator of type I interferon responses by modulating enhancer RNA transcription and promoter demethylation.

bioRxiv · Jan 14, 2023Immunology

An epigenetic memory of inflammation controls context-dependent lineage plasticity in the pancreas

D. J. Falvo, A. Grimont, P. Zumbo, J. L. Yang, A. Osterhoudt, G. Pan, A. F. Rendeiro, J. E. Wilkinson, F. Dündar, O. Elemento, R. K. Yantiss, D. Betel, R. Koche, R. Chandwani

This study shows that inflammation leaves an epigenetic memory in pancreatic acinar cells, affecting their lineage plasticity and tumorigenesis in response to subsequent stress.

bioRxiv · Nov 1, 2021Cancer Biology

Pancreatic cancer prognosis is predicted by a novel ATAC-array technology for assessing chromatin accessibility

S. Dhara, S. Chhangawala, H. Chintalapudi, G. Askan, V. Aveson, A. L. Massa, L. Zhang, A. P. Makohon-Moore, N. Lecomte, J. P. Melchor, J. Bermeo, A. Cardenas, S. Sinha, D. Glassman, R. Nicolle, , S. D. Leach

The paper develops ATAC-Array, a low-cost chromatin accessibility assay, and shows it predicts pancreatic cancer prognosis based on chromatin accessibility patterns.

bioRxiv · Jan 21, 2021Cancer Biology