Author

R. Coelho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

D. Alonso· 2 shared F. Jacob· 2 shared F. Singer· 2 shared N. Periolo· 2 shared S. Kehl· 2 shared V. Heinzelmann-Schwarz· 2 shared A. Bertolini· 1 shared A. C. F. Amaral· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

D. Alonso

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis

R. Coelho, B. Seashore-Ludlow, S. Schutz, F. Christopher Lombardo, E. Moussaud-Lamodiere, R. Casanova, J. Ficek-Pascual, K. Brunhilde Labrosse, M. Hensle, M. Lopez-Nunez, N. Rimmer, A. Fedier, R. Lima, C. Montavon Sartorius, C. Kurzeder, , F. Jacob

This study shows SMAC mimetics overcome apoptotic resistance in ovarian cancer by targeting the MSLN-TNF alpha axis, enhancing cell death and synergizing with chemotherapy.

bioRxiv · Jan 24, 2024 · PreprintCancer Biology

Andes virus genome mutations that are likely associated with animal-model attenuation and human person-to-person transmission

C. Bellomo, D. Alonso, U. Perez-Sautu, K. Prieto, S. Kehl, R. Coelho, N. Periolo, N. Di Paola, N. Ferressini-Gerpe, J. H. Kuhn, M. Sanchez-Lockhart, G. F. Palacios, V. Martinez

The paper identifies genome mutations in Andes virus associated with attenuation in animal models and increased human transmissibility.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer

A. Dondi, U. Lischetti, F. Jacob, F. Singer, N. Borgsmueller, R. Coelho, Tumor Profiler Consortium, V. Heinzelmann-Schwarz, C. Beisel, N. Beerenwinkel

This study uses long-read single-cell RNA sequencing to detect isoforms and genomic alterations in ovarian cancer, revealing novel isoforms, cell type-specific expression patterns, and gene fusions.

bioRxiv · Dec 12, 2022Cancer Biology

Emerging Hantaviruses in Central Argentina: first case of Hantavirus Pulmonary Syndrome caused by Alto Paraguay Virus and a novel orthohantavirus in Scapteromys aquaticus rodent.

C. M. Bellomo, D. Alonso, T. Ricardo, R. Coelho, S. Kehl, N. Periolo, N. Casas, L. C. Bergero, M. A. Previtali, V. P. Martinez

bioRxiv · Jun 13, 2021Pathology

A screening of the MMV Pathogen Box(R) reveals new potential antifungal drugs against the etiologic agents of chromoblastomycosis

R. Coelho, L. S. Joffe, G. M. Alves, M. H. G. Figueiredo-Carvalho, F. Brito-Santos, A. C. F. Amaral, M. L. Rodrigues, R. Almeida-Paes

This study screens the MMV Pathogen Box(R) to identify antifungal compounds effective against chromoblastomycosis agents, finding synergistic effects with existing drugs.

PLOS ONE · May 13, 2020Peer-reviewedMicrobiology