M. L. Rodrigues

Extracellular vesicles produced during fungal infection in humans are immunologically active

This study identifies and characterizes extracellular vesicles from human fungal infections, showing their role in modulating host immune responses through metabolite-mediated polarization of macrophages.

Monoclonal antibodies against cell wall chitooligomers as accessory tools for the control of cryptococcosis

This study develops monoclonal antibodies against chitooligomers that enhance antifungal efficacy against Cryptococcus neoformans in vitro and in a mouse model.

Extracellular vesicles regulate yeast growth, biofilm formation, and yeast-to-hypha differentiation in Candida albicans

This study shows that extracellular vesicles from Candida albicans inhibit biofilm formation, yeast-to-hypha differentiation, and virulence by altering gene expression and morphology.

Phytotoxic tryptoquialanines produced in vivo by Penicillium digitatum are exported in extracellular vesicles

This study shows that Penicillium digitatum exports tryptoquialanine A, a phytotoxic alkaloid, in extracellular vesicles during citrus infection, inhibiting seed germination and causing tissue damage.

Revisiting Cryptococcus extracellular vesicles properties and their use as vaccine platforms

This paper characterizes the structural and compositional features of Cryptococcus extracellular vesicles and demonstrates their potential as vaccine candidates.

Characterization of extracellular vesicles produced by Aspergillus fumigatus protoplasts

This study characterizes extracellular vesicles from Aspergillus fumigatus protoplasts, showing they are produced across morphological stages and contain proteins and glycans related to metabolism and pathogenesis.

A screening of the MMV Pathogen Box(R) reveals new potential antifungal drugs against the etiologic agents of chromoblastomycosis

This study screens the MMV Pathogen Box(R) to identify antifungal compounds effective against chromoblastomycosis agents, finding synergistic effects with existing drugs.

Extracellular vesicle-mediated RNA release in Histoplasma capsulatum

This study identifies strain-specific RNA content in extracellular vesicles from two Histoplasma capsulatum isolates, highlighting strain differences and potential miRNA-like molecules.