R. D. Dar

Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation

This study shows that monocyte-to-macrophage differentiation and redox changes influence HIV latency differently in cell types, with macrophages being more responsive to redox modulators.

Monitoring Reactivation of Latent HIV by Label-Free Gradient Light Interference Microscopy

This study uses label-free GLIM to quantify HIV reactivation in single cells by analyzing morphological changes, finding specific dry mass and diameter thresholds associated with latency and reactivation.

A transient heritable memory regulates HIV reactivation from latency

The paper shows that HIV-1 reactivation from latency is regulated by a transient heritable memory in T cells, revealed through fluctuation assays and mathematical modeling.

A Feedback Motif that Breaks the Fundamental Limit on Noise Suppression to Stabilize Fate

The paper identifies a feedback motif in HIV that suppresses noise more effectively than traditional methods, stabilizing cellular commitment to the active-replication state.