Author

R. D. Weeratna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

D. Bloemberg· 2 shared S. McComb· 2 shared T. Nguyen· 2 shared A. Marcil· 1 shared C. Gadoury· 1 shared D. Sosa-Miranda· 1 shared K. A. Henry· 1 shared Q. Zhu· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

D. Bloemberg

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 30, 2020

Antigenic Sensitivity of Membrane-Proximal Targeting Chimeric Antigen Receptors can be Fine-Tuned through Hinge Truncation

S. McComb, T. Nguyen, K. A. Henry…·R. D. Weeratna

This study shows that truncating the CD8 hinge domain in CARs can finely tune antigen sensitivity, improving selectivity for tumor cells over healthy ones.

DOI 10.1101/2020.10.30.360925

humanproteomics

𝕏 PostBluesky

BioengineeringbioRxivMar 25, 2020

Self-cutting and integrating CRISPR plasmids (SCIPs) enable targeted genomic integration of large genetic payloads for rapid cell engineering

D. Bloemberg, D. Sosa-Miranda, T. Nguyen…·S. McComb

This paper introduces SCIPs, CRISPR plasmids that integrate themselves at targeted genomic sites, enabling efficient and programmable gene editing in mammalian cells.

DOI 10.1089/crispr.2020.0090

mousehuman

𝕏 PostBluesky