Author

R. de Menezes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:long-read sequencing· 1 Approach:mixed model· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

A. Okonska· 1 shared E. Felley-Bosco· 1 shared E. Smit· 1 shared I. Van der Meulen-Muileman· 1 shared L. Penengo· 1 shared M. Blijlevens· 1 shared M. Ronner· 1 shared O. van Tellingen· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Okonska

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Author profile →

2 papers

Recent·Most cited

Reanalysis of in vivo drug synergy validation study rules out synergy in most cases

O. van Tellingen, R. de Menezes

This paper reanalyzes an in vivo drug synergy study and finds that most drug pairs do not show statistically significant synergy when using appropriate statistical methods.

bioRxiv · Nov 13, 2020Pharmacology & Toxicology

Genome-wide silencing screen in mesothelioma cells reveals that loss of function of BAP1 induces chemoresistance to ribonucleotide reductase inhibition: implication for therapy

A. Okonska, S. Buehler, V. Rao, M. Ronner, M. Blijlevens, I. Van der Meulen-Muileman, R. de Menezes, E. Smit, W. Weder, R. Stahel, L. Penengo, V. van Beusechem, E. Felley-Bosco

The paper identifies BAP1's role in regulating RRM2 during replication stress, showing that BAP1 loss increases chemoresistance to ribonucleotide reductase inhibitors in mesothelioma cells.

bioRxiv · Jul 31, 2018Cancer Biology