Asbestos accelerates disease onset in a genetic model of Malignant Pleural Mesothelioma
P. Farahmand, K. Gyuraszova, C. Rooney, X. L. Raffo-Iraolagoitia, E. Johnson, T. Chernova, T. Monteverde, K. Blyth, R. Duffin, L. M. Carlin, D. Lewis, J. Le Quesne, M. MacFarlane, D. J. Murphy
This study shows asbestos accelerates mesothelioma onset and increases tumor burden in a genetic mouse model, with increased macrophage infiltration, but macrophage suppression did not improve survival.
bioRxiv · Jun 16, 2020Cancer Biology