Author

D. Lewis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Organism:Drosophila· 1 Approach:statistical model· 1

Frequent Co-Authors

A. J. Simpson· 1 shared A. Rostron· 1 shared A. S. Mirchandani· 1 shared A. Webster· 1 shared A. Zhang· 1 shared C. C. Bain· 1 shared C. Pridans· 1 shared C. Pugh· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

A. J. Simpson

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Author profile →

4 papers

Recent·Most cited

Shifted levels of sleep and activity under darkness as mechanisms underlying ectoparasite resistance

J. B. Benoit, O. M. Ajayi, A. Webster, K. Grieshop, D. Lewis, H. Talbott, J. Bose, M. Polak

This study shows that mite-resistant Drosophila melanogaster lines exhibit reduced sleep, increased activity, and metabolic gene expression, but decreased starvation resistance under darkness.

bioRxiv · Oct 30, 2023 · PreprintEvolutionary Biology

Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence

A. S. Mirchandani, S. J. Jenkins, C. C. Bain, H. Lawson, P. Coelho, F. Murphy, D. Griffith, A. Zhang, M. A. Sanchez-Garcia, L. Reyes, T. Morrison, S. Arienti, P. Sadiku, E. Watts, R. Dickinson, , S. Walmsley

This study shows hypoxia suppresses type I interferon signaling in ALI, leading to monocytopenia and unchecked inflammation, which can be mitigated by CSF1 administration.

bioRxiv · Mar 11, 2022 · PreprintCell Biology

Frequency dependent growth of bacteria in living materials

D. Lewis, T. Gong, Y. Xu, C. Tan

This study investigates how bacteria grow in 3D hydrogels and finds that their growth depends on disturbance frequency and hydrogel density, explained through stochastic resonance theory.

bioRxiv · Feb 22, 2022Biophysics

Asbestos accelerates disease onset in a genetic model of Malignant Pleural Mesothelioma

P. Farahmand, K. Gyuraszova, C. Rooney, X. L. Raffo-Iraolagoitia, E. Johnson, T. Chernova, T. Monteverde, K. Blyth, R. Duffin, L. M. Carlin, D. Lewis, J. Le Quesne, M. MacFarlane, D. J. Murphy

This study shows asbestos accelerates mesothelioma onset and increases tumor burden in a genetic mouse model, with increased macrophage infiltration, but macrophage suppression did not improve survival.

bioRxiv · Jun 16, 2020Cancer Biology