Author

R. Ficner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:bacteria (other)· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. Stuelke· 3 shared A. Dickmanns· 2 shared C. Herzberg· 2 shared D. Wicke· 2 shared A. Chernev· 1 shared A. Filosa· 1 shared A. Marintchev· 1 shared A. Poehlein· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

J. Stuelke

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Molecular basis for the interactions of eIF2β with eIF5, eIF2B, and 5MP1 and their regulation by CK2

P. A. Wagner, M. Song, R. Ficner, B. Kuhle, A. Marintchev

This study investigates the molecular interactions of eIF2β with eIF5, eIF2B, and 5MP1 using crystallography and NMR, revealing binding sites and regulatory roles of CK2 phosphorylation.

bioRxiv · Apr 25, 2024Biochemistry

The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis

D. Wicke, P. Neumann, M. Goessringer, A. Chernev, A. Poehlein, R. Daniel, H. Urlaub, R. K. Hartmann, R. Ficner, J. Stuelke

The paper identifies RnpM (YlxR) as a novel modulator of RNase P activity in B. subtilis, reducing its ability to process pre-tRNAs.

bioRxiv · Jul 28, 2023 · PreprintMicrobiology

Ornithine is the central intermediate in the arginine degradative pathway and its regulation in Bacillus subtilis

R. Warneke, T. B. Garbers, C. Herzberg, G. Aschenbrandt, R. Ficner, J. Stuelke

This paper identifies ornithine as the central intermediate in the arginine and citrulline degradation pathway in Bacillus subtilis and shows it activates the transcription regulator RocR.

bioRxiv · Apr 21, 2023 · PreprintMicrobiology

A rendezvous of two second messengers: The c-di-AMP receptor protein DarB controls (p)ppGpp synthesis in Bacillus subtilis

L. Krueger, C. Herzberg, D. Wicke, H. Baehre, J. L. Heidemann, A. Dickmanns, K. Schmitt, R. Ficner, J. Stuelke

This study identifies DarB as a c-di-AMP receptor that interacts with Rel to regulate (p)ppGpp synthesis in Bacillus subtilis under low potassium conditions.

bioRxiv · Aug 27, 2020Microbiology

Mutations in nucleoporin NUP88 cause lethal neuromuscular disorder

E. Bonnin, P. Cabochette, A. Filosa, R. Juehlen, S. Komatsuzaki, M. Hezwani, A. Dickmanns, V. Martinelli, M. Vermeersch, L. Supply, N. Martins, L. Pirenne, G. Ravenscroft, M. Lombard, S. A. Port, , B. Fahrenkrog

This study identifies biallelic NUP88 mutations as a cause of lethal fetal akinesia deformation sequence (FADS) and shows their effects on neuromuscular development in zebrafish and human cells.

bioRxiv · Aug 14, 2018Cell Biology