Author

R. Flick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

E. A. Edwards· 4 shared L. Lomheim· 2 shared S. Gaspard· 2 shared S. Rambinaising· 2 shared A. Savchenko· 1 shared A. Starostine· 1 shared C. Jean-Marius· 1 shared D. J. Philpott· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

E. A. Edwards

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Structural and functional analyses of SARS-CoV-2 Nsp3 and its specific interactions with the 5' UTR of the viral genome

S. Lemak, T. Skarina, R. Flick, D. T. Patel, P. J. Stogios, A. Savchenko

This study analyzes the structural and functional interactions of SARS-CoV-2 Nsp3 with the 5' UTR of the viral genome, identifying key domains involved in binding and translocation.

bioRxiv · May 9, 2024Microbiology

Heterologous expression of Dehalobacter spp. respiratory reductive dehalogenases in Escherichia coli

K. Picott, R. Flick, E. A. Edwards

This paper develops a method to express reductive dehalogenases from Dehalobacter in E. coli, validated across six enzymes with varying sequence identities.

bioRxiv · Oct 6, 2021Microbiology

Identification of a fully dechlorinated product of chlordecone in soil microcosms and enrichment cultures

L. Lomheim, R. Flick, S. Rambinaising, S. Gaspard, E. A. Edwards

The paper identifies a fully dechlorinated product of chlordecone in soil microcosms, showing complete dechlorination is possible.

bioRxiv · Mar 3, 2021Microbiology

Evidence for extensive anaerobic dechlorination and transformation of the pesticide chlordecone (C10Cl10O) by indigenous microbes in microcosms from Guadeloupe soil

L. Lomheim, L. Laquitaine, S. Rambinaising, R. Flick, A. Starostine, C. Jean-Marius, S. Gaspard, E. A. Edwards

This study shows that indigenous microbes in Guadeloupe soil can extensively dechlorinate chlordecone under anaerobic conditions, removing up to 9 chlorine atoms and producing degradation products.

bioRxiv · Oct 26, 2019Microbiology

Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress

R. Molinaro, R. Flick, D. J. Philpott, S. E. Girardin

This study shows that trace peptidoglycan in serum triggers NOD-dependent cytokine responses to ER stress via intracellular Ca2+ changes and endocytosis.

bioRxiv · Feb 13, 2019Immunology

Interspecies malate-pyruvate shuttle drives amino acid exchange in organohalide-respiring microbial communities

P.-H. Wang, K. Correia, H.-C. Ho, N. Venayak, K. Nemr, R. Flick, R. Mahadevan, E. A. Edwards

This study identifies an interspecies malate-pyruvate shuttle in microbial communities that enables amino acid exchange under redox constraints.

bioRxiv · Aug 1, 2018Microbiology