Author

R. Hartley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. I. Lamond· 1 shared A. Islam· 1 shared A. Kellmyer· 1 shared A. Moore· 1 shared A. Pawellek· 1 shared B. D. Ficher· 1 shared F. DiGiorgio· 1 shared G. Moura-Letts· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. I. Lamond

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2 papers

Recent·Most cited

Abuse liability, antinociceptive, and discriminative stimulus properties of IBNtxA

A. Islam, M. A. Rahman, M. B. Brenner, A. Moore, A. Kellmyer, H. Buechler, F. DiGiorgio, V. Verchio, L. McCracken, M. Sumi, R. Hartley, J. R. Lizza, G. Moura-Letts, B. D. Ficher, T. M. Keck

This study evaluates the analgesic, rewarding, and discriminative stimulus properties of IBNtxA, finding it produces potent antinociception with low abuse liability due to κ agonist effects.

bioRxiv · May 30, 2020Pharmacology & Toxicology

Characterisation Of The Biflavonoid Hinokiflavone As A Pre-mRNA Splicing Modulator That Inhibits SENP

A. Pawellek, U. Ryder, T. Tammsalu, L. J. King, H. Kreinin, T. Ly, R. T. Hay, R. Hartley, A. I. Lamond

This study identifies hinokiflavone as a splicing inhibitor that modulates alternative splicing by inhibiting SUMO protease SENP1 and altering SUMOylation of splicing factors.

bioRxiv · Apr 1, 2017Biochemistry