S. M. Hanson

Promoter and Gene-Body RNA-Polymerase II co-exist in partial demixed condensates

This study investigates RNA polymerase II condensates in C. elegans using simulations and experiments, showing they exhibit LCST behavior and form distinct phases during transcription.

Extracting thermodynamic properties from van 't Hoff plots with emphasis on temperature-sensing ion channels

The paper introduces a mathematical framework to extract thermodynamic properties from van 't Hoff plots for temperature-sensing TRP channels, improving accuracy over previous methods.

Molecular dynamics simulations illuminate the role of sequence context in the ELF3-PrD-based temperature sensing mechanism in plants

The paper uses molecular dynamics simulations to show how sequence context and polyQ tract length affect temperature-dependent condensate formation in ELF3-PrD, influencing plant growth responses.

A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

This study shows that phosphorylation of Aurora A's activation loop activates the kinase without shifting the DFG-In state population, and that a DFG-Out subpopulation is important for optimized substrate binding kinetics.

An open library of human kinase domain constructs for automated bacterial expression

This paper presents a library of 52 human kinase domain constructs expressed in bacteria using phosphatase coexpression, enabling high-throughput biochemical and biophysical studies.