R. Law

Identification of Lactuca sativa transcription factors impacting resistance to Botrytis cinerea through predictive network inference

The paper identifies transcription factors in lettuce that influence resistance to Botrytis cinerea by inferring gene regulatory networks from time-series expression data.

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV

This study evaluates the immunogenicity of COVID-19 vaccines in older people with HIV and their impact on HIV reservoirs, finding that three doses are needed for optimal neutralizing responses but vaccines may increase HIV reservoirs in those with persistent viremia.

Longitudinal Assessment of SARS-CoV-2 Specific T Cell Cytokine-Producing Responses for 1 Year Reveals Persistence of Multi-Cytokine Proliferative Responses, with Greater Immunity Associated with Disease Severity

This study tracks SARS-CoV-2-specific T cell cytokine responses over one year, finding persistent multi-cytokine production with greater immunity linked to disease severity.

Maternal transmission as a microbial symbiont sieve, and the absence of lactation in male mammals

This paper uses mathematical models to show that uniparental vertical transmission of the microbiome acts as a sieve against deleterious symbionts, leading to selection against male lactation in mammals.

Fishing for biodiversity by balanced harvesting

This paper shows that balanced harvesting, where fishing mortality is scaled with species production rates, can protect rarer species while allowing exploitation of more productive ones in marine ecosystems.

Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B

This paper evaluates a SARS-CoV-2 mRNA vaccine, PTX-COVID19-B, showing it is safe, effective, and induces strong immune responses in mice and hamsters, with ongoing human clinical trials.