Author

P. Budylowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Mubareka· 4 shared A. Banerjee· 3 shared A. J. McGeer· 3 shared A.-C. Gingras· 3 shared K. Colwill· 3 shared K. Mossman· 3 shared L. Yip· 3 shared M. A. Ostrowski· 3 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersImmunology

S. Mubareka

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV

V. A. Matveev, E. Z. Mihelic, E. Benko, P. Budylowski, S. Grocott, T. Lee, C. S. Korosec, K. Colwill, H. Stephenson, R. Law, L. A. Ward, S. Sheikh-Mohamed, G. Mailhot, M. Delgado-Brand, A. Pasculescu, , M. Ostrowski

This study evaluates the immunogenicity of COVID-19 vaccines in older people with HIV and their impact on HIV reservoirs, finding that three doses are needed for optimal neutralizing responses but vaccines may increase HIV reservoirs in those with persistent viremia.

bioRxiv · Jun 14, 2023Immunology

Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B

J. Liu, P. Budylowski, R. Samson, B. D. Griffin, G. Babuadze, B. Rathod, K. Colwill, J. A. Abioye, J. A. Schwartz, R. Law, L. Yip, S. K. Ahn, S. Chau, M. Naghibosadat, Y. Arita, , M. A. Ostrowski

This paper evaluates a SARS-CoV-2 mRNA vaccine, PTX-COVID19-B, showing it is safe, effective, and induces strong immune responses in mice and hamsters, with ongoing human clinical trials.

bioRxiv · May 11, 2021Immunology

A simple protein-based surrogate neutralization assay for SARS-CoV-2

K. T. Abe, Z. Li, R. Samson, P. Samavarchi-Tehrani, E. J. Valcourt, H. Wood, P. Budylowski, A. P. Dupuis, R. C. Girardin, B. Rathod, K. Colwill, A. J. McGeer, S. Mubareka, J. L. Gommerman, Y. Durocher, , A.-C. Gingras

The paper introduces a protein-based assay to detect neutralizing antibodies against SARS-CoV-2, showing it correlates with traditional viral neutralization tests.

bioRxiv · Jul 10, 2020Immunology

Experimental and natural evidence of SARS-CoV-2 infection-induced activation of type I interferon responses

A. Banerjee, N. El-Sayes, P. Budylowski, D. Richard, H. Maan, J. Aguiar, K. Baid, M. R. D'Agostino, J. C. Ang, B. J.- M. Tremblay, S. Afkhami, M. Karimzadeh, A. T. Irving, L. Yip, M. A. Ostrowski, , K. Mossman

This study shows SARS-CoV-2 infection induces a mild type I IFN response in vitro and in moderate COVID-19 cases, and cannot inhibit exogenous IFN induction.

bioRxiv · Jun 18, 2020Immunology

Isolation, sequence, infectivity and replication kinetics of SARS-CoV-2

A. Banerjee, J. A. Nasir, P. Budylowski, L. Yip, P. Aftanas, N. Christie, A. Ghalami, K. Baid, A. R. Raphenya, J. A. Hirota, M. S. Miller, A. J. McGeer, M. A. Ostrowski, R. A. Kozak, A. G. McArthur, , S. Mubareka

The paper isolates SARS-CoV-2 from two patients, sequences the virus, and tests its infectivity in human immune cells, finding that PBMCs are not permissive to infection.

bioRxiv · Apr 11, 2020 · PreprintMicrobiology