Author

R. Lawrence

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Organism:human· 1 Assay:protein structure· 1 Assay:structural biology· 1

Frequent Co-Authors

L. Wang· 2 shared P. Walter· 2 shared A. Anand· 1 shared A. Deal· 1 shared A. Frost· 1 shared A. Gonzalez-Beltran· 1 shared A. Kenall· 1 shared A. Lister· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

L. Wang

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling

R. Lawrence, S. Shoemaker, A. Deal, S. Sangwan, A. Anand, L. Wang, S. Marqusee, P. Walter

The paper identifies a Switch-Helix in eIF2B that allosterically regulates ISR signaling and is conserved across species.

bioRxiv · Dec 22, 2022 · PreprintBiochemistry

Viral Evasion of the Integrated Stress Response Through Antagonistic eIF2-P Mimicry

M. Schoof, L. Wang, J. Z. Cogan, R. Lawrence, M. Boone, J. D. Wuerth, A. Frost, P. Walter

This study shows that SFSV NSs protein evades the ISR by competing with eIF2-P for binding to eIF2B, preserving its activity and allowing viral protein synthesis.

bioRxiv · Jun 7, 2021Biochemistry

FAIRsharing, a cohesive community approach to the growth in standards, repositories and policies

S.-A. Sansone, P. McQuilton, P. Rocca-Serra, A. Gonzalez-Beltran, M. Izzo, A. Lister, M. Thurston, D. Batista, R. Granell, M. Adekale, D. Dauga, E. Ganley, S. Hodson, R. Lawrence, V. Khodiyar, , Lynch

The paper introduces FAIRsharing, a community-driven resource that evaluates and promotes standards, databases, and repositories to improve data reuse and interoperability in research.

bioRxiv · Sep 26, 2018 · PreprintScientific Communication & Education