Author

M. Boone

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1 Plant Biology· 1 Zoology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Organism:multiple species· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. Schoof· 3 shared P. Walter· 3 shared A. Frost· 2 shared L. Wang· 2 shared A. A. Anand· 1 shared A. F. Brilot· 1 shared A. M. Smith· 1 shared A. N. Rizo· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

M. Schoof

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Viral Evasion of the Integrated Stress Response Through Antagonistic eIF2-P Mimicry

M. Schoof, L. Wang, J. Z. Cogan, R. Lawrence, M. Boone, J. D. Wuerth, A. Frost, P. Walter

This study shows that SFSV NSs protein evades the ISR by competing with eIF2-P for binding to eIF2B, preserving its activity and allowing viral protein synthesis.

bioRxiv · Jun 7, 2021Biochemistry

eIF2B Conformation and Assembly State Regulate the Integrated Stress Response

M. Schoof, M. Boone, L. Wang, R. E. Lawrence, A. Frost, P. Walter

This study shows that eIF2B assembly and conformation regulate the ISR, with ISRIB affecting eIF2B through decamer stabilization and allosteric modulation.

bioRxiv · Dec 28, 2020Cell Biology

An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation

M. Schoof, B. Faust, R. A. Saunders, S. Sangwan, V. V. Rezelj, N. Hoppe, M. Boone, C. Billesboelle, C. Puchades, C. M. Azumaya, H. T. Kratochvil, M. Zimanyi, I. Deshpande, J. Liang, S. Dickinson, , Barile-H

This paper develops a potent synthetic nanobody that neutralizes SARS-CoV-2 by locking its Spike protein in an inactive conformation, enabling aerosol delivery as a prophylactic or therapeutic agent.

bioRxiv · Aug 8, 2020Biochemistry

Co-expressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts

S. Ramundo, Y. Asakura, P. A. A. Salomé, D. Strenkert, M. Boone, L. C. M. Mackinder, K. Takafuji, E. Dinc, M. Rahire, M. Crèvecoeur, L. Magneschi, O. Schaad, M. Hippler, M. C. Jonikas, S. Merchant, , P. Walter

The paper identifies a conserved TicToc supercomplex in chloroplast protein import across species, showing coordinated gene expression and essential functional roles.

bioRxiv · Jul 4, 2020Plant Biology

Evaluating the data quality of iNaturalist termite records

H. Hochmair, R. Scheffrahn, M. Basille, M. Boone

This study evaluates the quality of iNaturalist termite records compared to expert collections and finds they complement geographic coverage without significantly compromising data quality.

bioRxiv · Dec 3, 2019Zoology