Author

R. M. Derbali

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Evagelidis· 2 shared D. Susan-Resiga· 2 shared N. G. Seidah· 2 shared R. Essalmani· 2 shared A. Delpal· 1 shared A. Roubtsova· 1 shared B. Coutard· 1 shared C. Mapa· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. Evagelidis

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLRthat is shed by Furin

D. Susan-Resiga, E. Girard, R. Essalmani, A. Roubtsova, J. Marcinkiewicz, R. M. Derbali, A. Evagelidis, J. H. Byun, P. F. Lebeau, R. C. Austin, N. G. Seidah

This paper identifies ASGR1 as a novel PCSK9-independent ligand of liver LDLR that is shed by Furin, leading to reduced LDLR levels and LDL uptake.

bioRxiv · Apr 11, 2021Biochemistry

SARS-CoV-2 spike-glycoprotein processing at S1/S2 and S2' and shedding of the ACE2 viral receptor: roles of Furin and TMPRSS2 and implications for viral infectivity and cell-to-cell fusion

R. Essalmani, J. Jain, D. Susan-Resiga, U. Andreo, A. Evagelidis, R. M. Derbali, D. Huynh, F. Dallaire, M. Laporte, A. Delpal, P. Sutto-Ortiz, B. Coutard, C. Mapa, K. Wilcoxen, E. Decroly, , N. G. Seidah

This study investigates the roles of Furin and TMPRSS2 in SARS-CoV-2 spike protein processing and viral entry, showing their synergistic effects and suggesting combined inhibitors as antivirals.

bioRxiv · Dec 18, 2020 · PreprintBiochemistry